J&J Family of Companies Associate Scientist - Oncology In Vivo Pharmacology in Beerse, Belgium

The Associate Scientist will join the Oncology in vivo group efforts in the pharmacological characterization and development of small molecules and biologics including those that function as immune modulators for the treatment of cancer. Responsibilities include but are not limited to:

  • Design, execute and interpret complex in vivo studies for the validation and characterization of targets or therapeutic agents in the areas of oncology and tumor immunology

  • Establish and perform in vivo model development, target inhibition, efficacy, and pharmacokinetic/ pharmacodynamics (PK/ PD) biomarker studies in rodents

  • May perform bioluminescent imaging studies using molecular reporters or disseminated/ metastatic disease models

  • May contribute to ex vivo analysis of tumor or immune cells by FACS, IHC, ELISA, RT-PCR, or Luminex

  • Occasional weekend, evening, and holiday dosing/ animal monitoring required

  • Manage multiple in vivo experiments simultaneously

  • Analyze and present data in a clear presentation ready format

  • Contribute to various projects outside of his/her own, collaborate with stakeholders from all relevant functions, and keep up-to-date in the literature related to his/her field

  • Act as an expert resource on project teams, and demonstrate clear and professional verbal and written communication

Qualifications

  • Hiring level will be commensurate with education and experience.

  • Bachelor’s degree (BS/ BA) or equivalent (upper school/non-university) in the life sciences (molecular/ cellular biology, biochemistry, pharmacology, tumor immunology) with at least 4 years of relevant pharmaceutical or biotech industry/ lab/ academic experience OR a Master’s degree (MS) with at least 3 years of relevant experience is required.

  • Cell culture of cancer or immune cells is required.

  • Experience with oncology relevant rodent models - xenografts and syngeneic models are required; primary grafts, orthotopic models, humanized models, or genetically engineered tumor models are preferred.

  • Must have experience with small molecules and/or biologics.

  • Strong skills in dosing (po, iv, ip, routes), health monitoring, and data collection and analysis are required.

  • Experience with bioluminescent imaging, FACS, IHC, ELISA, RT-PCR, Westerns, or Luminex® is desirable.

  • Ability to effectively present scientific data and concepts to colleagues and teams is required, and experience presenting at external meetings is desirable.

  • Experience in writing technical drafts for IND (US-FDA) or CTA (EMA) filings is preferred.

Specific Requirements

  • Working fluency in English

  • Accreditation or Certification of Regularization by Federation of European Laboratory Animal Science Associations (FELASA), or similar foreign certification

Primary Location

Belgium-Antwerp-Beerse

Organization

Janssen Pharmaceutica N.V. (7555)

Job Function

R&D

Requisition ID

1700186093W